Could the latex of Semecarpus anacardium (Kiri Badulla) cause nephrotic syndrome?

Minimal change disease (MCD) accounts for 10-15% of primary nephrotic syndrome cases in adults [1]. Most cases are idiopathic. However, approximately 10% may have an identifiable cause. Secondary causes may include drugs, toxins, infections and tumours [2]. Non-steroidal anti-inflammatory drugs (NSAIDs) mercury, lithium and bee stings are some established causes of MCD. Although some plant products are known to cause nephrotoxicity, external contact of plant latex has not been reported as a nephrotoxin. We are reporting a possible case of an unusual cause of nephrotic syndrome following skin contact of latex of Semecarpus anacardium (SA). To the Editors: